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Document Details
Document Type
:
Article In Journal
Document Title
:
Study of Chemical Ligation Via 17-, 18- and 19-Membered Cyclic Transition States
Study of Chemical Ligation Via 17-, 18- and 19-Membered Cyclic Transition States
Document Language
:
English
Abstract
:
Unprotected S-acylated cysteine isopeptides containing alpha-, beta- or gamma-amino acid units have been synthesized, and their conversion to native hexapeptides by S- to the N-terminus ligations involving 17-, 18- and 19-membered cyclic transition states have been demonstrated both experimentally and computationally to be more favorable than intermolecular cross-ligations.
ISSN
:
1747-0277
Journal Name
:
CHEMICAL BIOLOGY & DRUG DESIGN
Volume
:
80
Issue Number
:
6
Publishing Year
:
1433 AH
2012 AD
Article Type
:
Article
Added Date
:
Tuesday, July 11, 2017
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
S Panda
Panda, S
Researcher
C El-Nachef
El-Nachef, C
Researcher
K Bajaj
Bajaj, K
Researcher
A Alyoubi,
Alyoubi,, A
Researcher
A Oliferenko
Oliferenko, A
Researcher
A Katritzky
Katritzky, A
Researcher
Files
File Name
Type
Description
42065.pdf
pdf
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