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Faculty of Medicine
Document Details
Document Type
:
Article In Journal
Document Title
:
Drug induced Tubulo-Interstitial Nephritis at King Khalid National Guard Hospital, Jeddah
Drug induced Tubulo-Interstitial Nephritis at King Khalid National Guard Hospital, Jeddah
Subject
:
Nephrology
Document Language
:
English
Abstract
:
Acute tubulo-interstitial nephritis (TIN) is a well known complication of many drugs such as antibiotics, diuretics, non-steroidal antiinflammatory drugs, therapeutic agents, and chemicals such lithium and platinum. It is characterized by a triad of rash, fever and eosinophilia. We present here the clinical features and management outcome of 8 cases encountered in our hospital over the last 5 years. Antibiotics were the inducing agent in 6 of the 8 cases, while the remaining two cases were induced by frusemide and lithium. The most common inducing antibiotic in our area was amoxycillin (4/8 cases). A case of drug-induced TIN by cefotaxime was encountered in the study, which we believe to the best of our knowledge is the first report of druginduced TIN by this antibiotic. All the patients made excellent recovery by the withdrawal of the inducing drug, steroid therapy and dialysis in some cases. A high index of suspicion is required to make an early diagnosis and to prevent renal damage. Clinical diagnosis can be confirmed by renal biopsy
ISSN
:
1319-1004
Journal Name
:
Medical Science Journal
Volume
:
9
Issue Number
:
1
Publishing Year
:
1421 AH
2001 AD
Article Type
:
Article
Added Date
:
Thursday, May 24, 2012
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
سعد الشهيب
Al-Shohaib, Saad
Researcher
Doctorate
Files
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Type
Description
33347.pdf
pdf
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