Document Type |
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Article In Journal |
Document Title |
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Changes in amino acid neurotransmitters in the CNS of developing rat due to thioridazine administration التغيرات الناشئة في الاحماض الامينية التي تعمل كناقلات عصبية في الجهازالعصبي المركزي للفأر الابيض النامي نتيجة الحقن بالثيريدازين |
Subject |
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Effect of thioridazine on the amino acid levels during brain development |
Document Language |
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English |
Abstract |
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The present investigation showed that, the daily i.p. injection of 10 mg/kg thioridazine decreased the levels of glutamic acid, glutamine, aspartic acid, asparagine, GABA,glycine, alanine and taurine, in both brain and spinal cord of albino rat at different postnatal ages. This decrease was relatively greated in brain, particularly in the level of glutamic acid, glutamine, glycine and taurine. Also, there was an increase of GOT and GPT levels. Also, there was adecrease in total protein content and a decrease in the activity of AchE due to thioridazine ingection |
ISSN |
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1319-0989 |
Journal Name |
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Arts and Humanities Journal |
Volume |
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1 |
Issue Number |
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23 |
Publishing Year |
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1414 AH
1992 AD |
Article Type |
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Article |
Added Date |
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Monday, January 3, 2011 |
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Researchers
سيد محمد راوي | Rawi, sayed mohamed | Investigator | Doctorate | rawisayed@yahoo.com |
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